If you're looking for a meeting place or a good stop around ½ or halfway between San Francisco and La Honda, you can try San Mateo, CA, which is about half an hour south of San Francisco, or about half an hour north of La Honda.
About ⅓ or a third of the way, you can stop at San Bruno, CA. This is about 18 minutes south of San Francisco.
About ⅔ or two thirds of the way, you can stop at Woodside Glens, CA. This is about half an hour south of San Francisco, or about half an hour north of La Honda.
About ¾ or three fourths of the way, you can stop at Searsville, CA. This is almost an hour south of San Francisco, or about 15 minutes north of La Honda.
If you drive straight through without stopping at all, the total distance is 45 miles. The distances shown above don't include local roads to get into each town, so if you're planning a long road trip, make sure you factor in traffic and road conditions, rest stop breaks, and interesting detours along the way. If you're in a rush, you can do the trip with zero stops, and your total travel time would be around 57 minutes.