If you're looking for a meeting place or a good stop around ½ or halfway between Rincon and Folly Beach, you can try Brewton, SC, which is almost an hour northeast of Rincon, or about 1 hour west of Folly Beach.
Other possible places to stop near the midpoint include Radnor, and Hickory Hill.
About ¼ or a fourth of the way, you can stop at Switzerland, SC. This is about half an hour northeast of Rincon.
About ⅓ or a third of the way, you can stop at Coosawhatchie, SC. This is almost an hour northeast of Rincon.
About ⅔ or two thirds of the way, you can stop at Ponpon, SC. This is about 1½ hours northeast of Rincon, or almost an hour west of Folly Beach.
About ¾ or three fourths of the way, you can stop at Baptist Hill, SC. This is about 1½ hours northeast of Rincon, or about half an hour west of Folly Beach.
If you drive straight through without stopping at all, the total distance is 115 miles. The distances shown above don't include local roads to get into each town, so if you're planning a long road trip, make sure you factor in traffic and road conditions, rest stop breaks, and interesting detours along the way. If you're in a rush, you can do the trip with zero stops, and your total travel time would be around 2 hours, 8 minutes.