If you're looking for a meeting place or a good stop around ½ or halfway between Pataskala and Pittsburgh, you can try Sewellsville, OH, which is about 1½ hours east of Pataskala, or about 1½ hours west of Pittsburgh.
About ¼ or a fourth of the way, you can stop at Bridgeville, OH. This is almost an hour east of Pataskala.
About ⅓ or a third of the way, you can stop at Cambridge, OH. This is almost an hour east of Pataskala.
About ⅔ or two thirds of the way, you can stop at Wheeling, WV. This is almost 2 hours east of Pataskala, or about 1 hour southwest of Pittsburgh.
About ¾ or three fourths of the way, you can stop at West Alexander, PA. This is about 2 hours east of Pataskala, or almost an hour southwest of Pittsburgh.
If you drive straight through without stopping at all, the total distance is 170 miles. The distances shown above don't include local roads to get into each town, so if you're planning a long road trip, make sure you factor in traffic and road conditions, rest stop breaks, and interesting detours along the way. If you're in a rush, you can do the trip with zero stops, and your total travel time would be around 2 hours, 46 minutes.