If you're looking for a meeting place or a good stop around ½ or halfway between Newark and Charlotte, you can try Richmond, VA, which is almost 5 hours southwest of Newark, or about 4½ hours northeast of Charlotte.
Other possible places to stop near the midpoint include Corbin, Lorne, Glen Allen, and Tuckahoe.
About ¼ or a fourth of the way, you can stop at Baltimore, MD. This is about 2½ hours southwest of Newark.
About ⅓ or a third of the way, you can stop at Washington, DC. This is about 3 hours southwest of Newark.
About ⅔ or two thirds of the way, you can stop at Henderson, NC. This is about 6½ hours southwest of Newark, or about 3 hours northeast of Charlotte.
About ¾ or three fourths of the way, you can stop at Durham, NC. This is about 7 hours southwest of Newark, or about 2½ hours northeast of Charlotte.
If you drive straight through without stopping at all, the total distance is 625 miles. The distances shown above don't include local roads to get into each town, so if you're planning a long road trip, make sure you factor in traffic and road conditions, rest stop breaks, and interesting detours along the way. If you're in a rush, you can do the trip with zero stops, and your total travel time would be around 9 hours, 27 minutes.