If you're looking for a meeting place or a good stop around ½ or halfway between Laguna Woods and Santa Clara, CA, you can try Semitropic, CA, which is almost 3 hours northwest of Laguna Woods, or a little over 3 hours southeast of Santa Clara, CA.
Other possible places to stop near the midpoint include Lost Hills, and Kettleman City.
About ¼ or a fourth of the way, you can stop at Martins, CA. This is about 1½ hours northwest of Laguna Woods.
About ⅓ or a third of the way, you can stop at Lamont, CA. This is a little over 2 hours northwest of Laguna Woods.
About ⅔ or two thirds of the way, you can stop at Cantua Creek, CA. This is about 4 hours northwest of Laguna Woods, or about 2 hours southeast of Santa Clara, CA.
About ¾ or three fourths of the way, you can stop at Los Banos, CA. This is about 4½ hours northwest of Laguna Woods, or about 1½ hours east of Santa Clara, CA.
If you drive straight through without stopping at all, the total distance is 391 miles. The distances shown above don't include local roads to get into each town, so if you're planning a long road trip, make sure you factor in traffic and road conditions, rest stop breaks, and interesting detours along the way. If you're in a rush, you can do the trip with zero stops, and your total travel time would be around 6 hours, 5 minutes.