If you're looking for a meeting place or a good stop around ½ or halfway between Kansas City and Humansville, you can try Creighton, MO, which is almost an hour southeast of Kansas City, or about 1 hour northwest of Humansville.
About ¼ or a fourth of the way, you can stop at Raymore, MO. This is about half an hour south of Kansas City.
About ⅓ or a third of the way, you can stop at Garden City, MO. This is almost an hour southeast of Kansas City.
About ¾ or three fourths of the way, you can stop at Deepwater, MO. This is about 1½ hours southeast of Kansas City, or about half an hour north of Humansville.
If you drive straight through without stopping at all, the total distance is 120 miles. The distances shown above don't include local roads to get into each town, so if you're planning a long road trip, make sure you factor in traffic and road conditions, rest stop breaks, and interesting detours along the way. If you're in a rush, you can do the trip with zero stops, and your total travel time would be around 1 hour, 54 minutes.