If you're looking for a meeting place or a good stop around ½ or halfway between Grosse Pointe Park and Lakewood, OH, you can try Fremont, OH, which is about 1½ hours south of Grosse Pointe Park, or a little over 1 hour west of Lakewood, OH.
Other possible places to stop near the midpoint include Cummings, Tousaint, Woodland Forest, Elmore, Genoa, Gibsonburg Junction, Busy Corners, and Hessville.
About ¼ or a fourth of the way, you can stop at Monroe, MI. This is almost an hour southwest of Grosse Pointe Park.
About ⅓ or a third of the way, you can stop at Toledo, OH. This is almost an hour southwest of Grosse Pointe Park.
About ⅔ or two thirds of the way, you can stop at Whitmore, OH. This is almost 2 hours south of Grosse Pointe Park, or about 1 hour west of Lakewood, OH.
About ¾ or three fourths of the way, you can stop at Berlin Heights Station, OH. This is about 2 hours south of Grosse Pointe Park, or almost an hour west of Lakewood, OH.
If you drive straight through without stopping at all, the total distance is 171 miles. The distances shown above don't include local roads to get into each town, so if you're planning a long road trip, make sure you factor in traffic and road conditions, rest stop breaks, and interesting detours along the way. If you're in a rush, you can do the trip with zero stops, and your total travel time would be around 2 hours, 45 minutes.