About ¼ or a fourth of the way, you can stop at Davis, LA. This is about 10 minutes southeast of Destrehan.
About ⅔ or two thirds of the way, you can stop at Waggaman, LA. This is about half an hour east of Destrehan, or about 14 minutes northwest of Estelle.
About ¾ or three fourths of the way, you can stop at Westwego, LA. This is about half an hour east of Destrehan, or about 10 minutes northwest of Estelle.
If you drive straight through without stopping at all, the total distance is 24 miles. The distances shown above don't include local roads to get into each town, so if you're planning a long road trip, make sure you factor in traffic and road conditions, rest stop breaks, and interesting detours along the way. If you're in a rush, you can do the trip with zero stops, and your total travel time would be around 41 minutes.