If you're looking for a meeting place or a good stop around ½ or halfway between Ashiaman and Dunkwa, you can try Akim Oda, Ghana, which is about 3 hours west of Ashiaman, or about 3½ hours east of Dunkwa.
About ⅓ or a third of the way, you can stop at Asamankese, Ghana. This is about 2 hours west of Ashiaman.
If you drive straight through without stopping at all, the total distance is 294 km. The distances shown above don't include local roads to get into each town, so if you're planning a long road trip, make sure you factor in traffic and road conditions, rest stop breaks, and interesting detours along the way. If you're in a rush, you can do the trip with zero stops, and your total travel time would be around 6 hours, 16 minutes.